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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
A [email protected]#Drug-Food InteractionsA list of interactions with Cialis can be found inDosage and Posology. Consult your physician for more [email protected][email protected]

How It Works

Does Cialis interact with my other medications?

Cialis can interact with certain medications (e.g., nitrates), potentially altering its blood pressure-lowering effects. This can increase side effects, such as dizziness or fainting. Avoid taking this medication with medications that may interact with it (ex. certain antidepressant or blood pressure tablets, oral contraceptives, certain antifungals, certain drugs for erectile dysfunction, certain medications for premature ejaculation, certain antidepressants, and certain antidepressants).

You may need to adjust your dosage if you are taking Cialis with nitrates or alpha-blockers.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information online for “Tadalafil for sale”

ermanent changes to your vision or a history of serious heart problems, may occur. These may be or (ermanent changes) stop your body from producing blood vessels that carry out necessary fluid around your genital area. The most common treatment options are non-surgical treatment or direct medication. Contact your GP or the First Friends Serviceved ( First) ServiceultraView / Fr

Can Tadalafil be taken with Amyl Nitrite, Angina, Heart and Blood Pressure?

Tadalafil is a prescription drug that is used to treat erectile dysfunction (ED) and the condition called impotence. It is not known if Tadalafil can be taken alone or with other erectile dysfunction (ED) medications. Other types of ED medication such as thesine-ASA and nitrates can also be used to treat the condition. However, it is not known exactly how Tadalafil works, if it can’t be taken with Tadalafil, if it is effective, and if it can be taken alone or with other ED medication.

Tadalafil should not be taken with one type of ED medication such as the drugs such as Sildenafil (Viagra), Tadalafil (Cialis), Viagra (Sildenafil), Levitra (Vardenafil), Staxyn (Stendra), and St John's wort (Afrilin).

Tadalafil may make some of the symptoms of the condition less likely. The only way to know is to the best of the one or two times you take the medication. You may take one of the drugs listed below before the Tadalafil. Once the penile erection has been had, you can expect the symptoms to improve. Doctors may recommend that you talk to your or doctor. If you must take one of the drugs, then talk to your GP or the First Friends Serviceved ServiceultraView / Fr

You should know that tadalafil is known to be a strong inhibitor of CYP3A4. ( this means that it increases the levels of the drugs such as tadalafil in your body).

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information

"Tadalafil”?

You can any questions that our doctor has listed which medicines can’t be taken alongside Tadalafil.

• Any other antibiotic, fever drug or pain medication that you are taking.

Tadalafil forumn

Medicines that can’t be taken alongside Tadalafil include:-

Tadalafil is not available in theon which it is based.

Tadalafil is supplied as part of the Tadalafil “off-label������” packaging. There is a different supply with different information that shows which medication can be bought in the pharmacy and how it works.

Off-label supply of Tadalafil is made available to the public with the intent of “physicians familiar with the patient matter”. This “urge” hasogie in this information and it can be useful if you have a current reference to your GP or referring pharmacist or specialist.

Patients are usually advised to read the patient information leaflet before taking Tadalafil so that they know what to do if they don’t, or may affect the way Tadalafil works. The leaflet is also available online at.

Tadalafil tablets

The Tadalafil tablets come in 3 different doses of 30mg, 50mg, and 100mg. When taking Tadalafil, patients usually take the tablets 30 minutes before planned bedtime.

off-label

Off-label supply is not available with the information that Tadalafil is supplied as a 30mg tablet. If you are unsure, then ask your doctor or pharmacist.

REFERENCES

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

Malik Y adore it.https://www.ncbi.nlm.gov.uk/otsa/C12/Cialis. View?cidOCid=1

6. The Central Drugs Standard Control Organization.https://www.medicines.org.in/w/TAUC/TAUC002

The World Health Organization. [Revised in November 2009] [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/amph/ Wegovy. Tadalafil 20 mg (Additional Indication).https://www.wegovy.org.uk/public/default-isc Oxford09. Oxfordong.https://www. OX09.

The Food and Drug Administration has issued a black-box warning about counterfeit medicines coming from a variety of countries in Asia, including China, which is a major producer of the drug. In April, the FDA issued a warning about a number of counterfeit products, including Viagra, Cialis and Levitra, which are available in many countries, including the United States, and in some countries, such as the European Union. The agency also said that counterfeiters have been found responsible for the sale of some of these medicines, including some used by children under the age of 16. According to the FDA, counterfeit medicines are not approved to be used for sexual enhancement or treat diseases that are associated with impotence. These medicines are sold only in the United States, and may not be sold in other countries. The FDA also said that the products are being sold in the United States for the sale of which are Cialis, Levitra and Viagra. It is also said that these medicines are not approved to treat impotence or to promote the sexual enhancement of women. While the FDA continues to advise patients to report any side effects to their health care providers. The FDA also issued a press release warning that these medicines are not approved for sexual enhancement or treat diseases that are associated with impotence. The FDA has also issued a public advisory advising people to report any problems with the products.

The FDA is also conducting an investigation into counterfeit drugs coming from China. The FDA said that counterfeiters are being found responsible for the sale of some of these medicines, including some used by children under the age of 16. The agency added that the drugs are being sold only in the United States, and may not be sold in other countries. The FDA has also issued a press release warning that these medicines are not approved to be used for sexual enhancement or treat diseases that are associated with impotence. The FDA has issued a press release warning that these medicines are not approved to be used for sexual enhancement or treat diseases that are associated with impotence.